Other ingredients: Gelatin, microcrystalline cellulose,
and magnesium stearate.
This product is manufactured to meet the stringent standards
of the US Pharmacopoeia for quality, purity, potency, & disintegration.
Made from pure, quality ingredients. Contains no sugar,
starch, yeast, wheat, corn, soy, egg, milk, artificial flavors, colors,
or preservatives.
As a dietary supplement, take one (1) or more capsules
per day with meals or as recommended by a health care professional. It
is recommended this product be taken with vitamins and minerals.
Do not refrigerate.
Keep out of reach of children.
Keep in a dry place, tightly capped.
Variation in the product color may occur.
Active L-Carnitine Formula
Pure, Elemental (active) L-Carnitine Fumarate for healthy
heart & brain tissue, lipid metabolism, and athletic support.
Each capsule contains Elemental L-Carnitine Fumarate 300
mg,
What Is Carnitine?
Carnitine is a naturally occurring amino acid metabolized
from Lysine and Methionine (with Vitamins B-6 and C) and synthesized in
the liver and kidneys. The food source is meat and milk and it is absent
in strict vegetarian diets. Carnitine is a necessary component of heart
and skeletal muscle tissue. It is involved in lipid metabolism, and it
functions to transport fatty acids across the inner mitochondrial membranes.
This amino acid is also essential for brain cells and healthy neurological
function, and it promotes longevity by helping to provide cells with the
necessary energy to function.
Carnitine deficiencies are common, and are evident in
two types of conditions. Those in which Myopathy is involved, note Carnitine
deficiencies in muscles, whereas systemic deficiencies are results of long
term diseases, such as renal failure, and Reye's syndrome. Low levels of
Camitine have been also noted in patients with diabetes, myocardial ischemia,
cancer and alcoholism. There are different types of Carnitine: Elemental
(active) L-Camitine Fumarate has an extra molecule of furnaric acid, that
helps maintain Krebs Cycle function, and Acetyl-Camitine crosses the blood
brain barrier quickly and aids in neurological function Carnitine supplementation
results in increased plasma and tissue levels of Carnitine.
Carnitine and Heart Function
In healthy heart tissue, Carnitine has adequate amounts
to provide sufficient fatty acids, which are the principal energy substrate
of the heart.
Camitine levels decrease in patients with acute and chronic
ischemic cardiopathy, including angina pectoris, myocardial infarction,
chronic coronary insufficiency, as well as heart failure. This causes the
heart to shift to Glucose metabolism to supply energy, resulting in over-utilization
of glycogen, thus depleting glycogen stores, which are necessary to supply
emergency energy to the heart.
Carnitine supplementation enables the facilitation of
fatty acid oxidation, preserving glycogen stores and restoring normal metabolic
conditions to the heart.
Supplementation of Camitine to patients with angina pectons
may improve exercise tolerance, help prevent arrhythmias, and may be beneficial
in patients with congestive heart failure as well. Camitine supplementation
may improve tachycardia and reduce signs and symptoms of ischemia in patients
with coronary artery disease,
Carnitine, Aceytl-Carnitine, and Brain and Neurological
Function.
- Carnitine and Acetyl-Camitine are present in the grey
matter of the central nervous system.
- Acetyl-Carnitine, the Ester form of Carnitine, is quickly
absorbed into the brain and has significant effect on healthy neurological
function, especially on age-related changes on dopamine receptors and amino
acid levels in the brain. Acetyl-Camitine protects neurons against oxidative
damage and may slow the progression of dementia in Alzheimees patients,
- Acetyl-Carnitine has a role in neuronal metabolism and
increases neurotrophic factors, and it may be beneficial with patients
who have peripheral neuropathies with pain.
Lipid Metabolism
- Camitine is involved in tat metabolism, and is the only
known substance that can lower harmful Triglyceddes, which can cause poor
circulation, myocardial infarction and kidney disease.
- Camitine transfers long chain fatty acids across the
mitochondrial membranes of cells, where they can be used as an energy source.
By mobilizing the fatty acids, it stimulates fat metabolism resulting in
fat reduction.
- Acetyl-Carnitine is also involved in lipid activity,
and has a positive effect on lowering cholesterol.
Athletic Performance
- Carnitine supplementation increases lipid metabolism
in muscles during physical activity, which leads to saving glycogen stores.
This helps prevent the breakdown of muscle tissue during prolonged & vigorous workouts and general athletic activities.
- Camitine increases energy, but without supplementation,
Carnitine pools become depleted due to strenuous activity. Acetyl-Carnitine
also has a beneficial effect on muscles, which is important for athletic
performance.
- Athletes administered Carnitine supplementation showed
increased performance in sports activities.
Additional Information Regarding Carnitine
- Low levels of Acetyl-Camitine have been documented in
infertile sperm.
- Camitine enhances liver function and the immune system.
- It naturally increases mental and physical energy.
- Some benefits have been noted in symptoms of Parkinson's
Disease and degenerative muscle conditions.
Some Benefits of Carnitine
- Bio-Recovery provides the purest, active L-Camitine to
insure effectiveness.
- Many Camitine products only state total molecular weight
of ingredients without providing the actual activity of the Carnitine.
Bio-Recovery provides all pure, Elemental (active) L-Camitine.
- L-Camitine Fumarate has an extra furnaric acid. molecule
to help Krebs' Cycle function.
References:
- Di Pasquale, M. Amino Acids and Proteins for the Athlete, The Anabolic
Edge, 1997.
- Heurtes, et al 'Respiratory Chain Enzymes in Muscle of Endurance Athletes,
Effect of L-Carnitine", Biochem. Biophys. Res. C.1992.
- Spagnoli A. et al "Long-term Acetyl-Camitine Treatment In Alzheimees
Disease". Neurology, 1991.
- Bruno, g et al, "Acetyl-L-Carnitine In Alzheimer Disease: A Short
Term Study on CSF Neurotransmitters and Neuropeptides, Alzheimers Disease
and Associated Disordors," 1995.
- Pepine, Carl J, "The Therapeutic Potential of Carnitine in Cardiovascular
Disease", Clinical Therapeutics, Feb. 1991.
- Crayhon, Robert M.S., The Carnitine Miracle. 1998,